In recent years, oncogenic drivers with sensitivity to targeted therapies (e.g., tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR) mutations, anaplastic lymphoma kinase (ALK) rearrangements, or other oncogenic abnormalities) have been discovered in NSCLC, leading to improvements in the outcome of oncogenic-driven NSCLC patients [3]. This evidence concerns the gene ALK and non-small cell lung carcinoma.