PTK2 and lung cancer: It was found that the mean nuclear FAK staining scores were significantly increased in lung cancer as compared to normal lung tissues, but without significant difference between NSCLC and SCLC (146.5 ± 61.4 vs. 130.4 ± 39.4 vs. 55.2 ± 19.5, respectively) (p < 0.01 only for comparison between normal and lung cancer) (Figure 4A), while mean nuclear phospho-FAK staining scores were significantly increased in SCLC as compared to NSCLC and normal lung samples (91 ± 47 vs. 37 ± 11 vs. 25 ± 12, respectively) (p < 0.01) (Figure 4B).