In support of these observations, increased expression of iNOS and Arg1, two genes commonly expressed by MDSCs, were also observed in prostatic tumor tissues of the Cdh1L/L:PtenL/L:PB-Cre4 compound mice in comparison with either PtenL/L:PB-Cre4 or Cdh1L/L:PB-Cre4 mice (S2C Fig). The gene discussed is ARG1; the disease is prostate neoplasm.