An increase in cell numbers with positive staining for MDSC markers, Cd11b and Gr-1, was also revealed in prostatic tumor lesions of Cdh1L/L:PtenL/L:PB-Cre4 compound mice compared to PtenL/L:PB-Cre4 mice (S2A3-4 Fig and S2B3-4 Fig). This evidence concerns the gene ITGAM and prostate neoplasm.