iPSCs‐derived neurospheres from schizophrenia patients carrying 22q11.2 micro‐deletions (Fig 6D) (Bundo et al, 2014; Maekawa et al, 2015; Toyoshima et al, 2016) showed a significant increase in CBS mRNA compared to those derived from control subjects (Fig 6E). This evidence concerns the gene CBS and schizophrenia.