Although we revealed the elevated sulfide stress in schizophrenia pathophysiology, in the light of Mpst from our proteomics study, upregulation of a combination of the three genes encoding H2S/polysulfides‐synthesizing enzymes, namely, Mpst (MPST), Cbs (CBS), and Cth (CTH), was observed in mouse models and human schizophrenia samples. This evidence concerns the gene CBS and schizophrenia.