IL10 and colitis: Consistent with our results, Mishima et al also report that microbiota‐induced intestinal B10 cells ameliorated chronic T cell‐mediated colitis in IL‐10 deficient background mice.31 However, since all experiments in the current study are carried out in IL10−/− mice, it is not clear whether ManLAM‐treated B cells would also play a role in IL10‐sufficient animals.