Currently, ex vivo [111In]In-oxine-labelled autologous CD8+ T-cells, isolated using CD8+ specific magnetic beads, are used to evaluate T-cell infiltration in early stage non-small cell lung cancer patients who receive anti-PD-L1 immunotherapy in neo-adjuvant setting (NCT03853187). The gene discussed is CD274; the disease is non-small cell lung carcinoma.