MiR‐194 is a kind of the p53 responsive miRNAs, which has been reported to significantly suppress the proliferation and invasion of several cancer cells and acts as a tumour suppressor.42, 43 MiR‐194‐5p has been found to be low expressed in glioma tissue and overexpression of miR‐194‐5p suppresses invasion and epithelial‐mesenchymal transition of glioma cells.44 Under serum‐deprived condition, miR‐194‐5p was involved in the regulation of endothelial gene expression as well as the functional angiogenic activity.21 In GECs, we found that miR‐194‐5p was low expressed. This evidence concerns the gene TP53 and central nervous system cancer.