MEG3 and cancer: Furthermore, it has been shown that LncRNAs are key regulators of cancer metabolism [45,46], and several LncRNAs have been implicated in the development of cancer, including LINC01554, LINC00689, MAFG-AS1, highly up-regulated in liver cancer gene (HULC), FEZF1 antisense RNA 1 (FEZF1-AS1), lincRNA-p21, MEG3, HOXB cluster antisense RNA 3 (HOXB-AS3), tumor protein 53 target gene 1 (TP53TG1) and lncRNA regulator of reprogramming (linc-RoR) [47].