ABCB1 and hematologic disorder: In addition, overexpression of BCL11A may cooperate with ATP-binding cassette subfamily B member 1 (MDR1) [76], Mdm2, phosphatase and tensin homolog (Pten) [74], and MLL-AF9 [26], DNA methyltransferase 3α (DNMT3A) R882 mutation and FLT3-ITD (internal tandem duplication) mutation [66] to participate in hematological malignancies.