Wu Wu J J Qiu Qiu Y Y Zhang Zhang L L Sun Sun Q Q Qiu Qiu X X He He Y Y Association of estrogen receptor gene polymorphisms with susceptibility to adolescent idiopathic scoliosis Association of estrogen receptor gene polymorphisms with susceptibility to adolescent idiopathic scoliosis Spine. This evidence concerns the gene ESR1 and idiopathic scoliosis.