Wu Wu J J Qiu Qiu Y Y Zhang Zhang L L Sun Sun Q Q Qiu Qiu X X He He Y Y Association of estrogen receptor gene polymorphisms with susceptibility to adolescent idiopathic scoliosis Association of estrogen receptor gene polymorphisms with susceptibility to adolescent idiopathic scoliosis Spine. The gene discussed is ESR1; the disease is adolescent idiopathic scoliosis.