In a study done by Chen et al., (2013), who found that SALL4 gene expression differ significantly with AML FAB subtypes and the frequency of SALL4 expression was in M2 (86.7%, 13/15) > M3 (75.0%, 6/8) > M1 (60.0%, 3/5) > M4 (14.3%, 1/7), and the difference among the 4 groups was statistically significant (P = 0.008). Here, SALL4 is linked to acute myeloid leukemia.