Our results differ than other study carried out by Ma and his colleagues, 2013 on SALL4 gene expression in 35 AML patients and revealed a significantly positive correlation between the level of SALL4 expression and the status of SALL4 SALL4 hypomethylation (r=0.501, P=0.002); where SALL4 gene is frequently hypomethylated in AML and hypomethylation was correlated with the high expression of SALL4 gene. This evidence concerns the gene SALL4 and acute myeloid leukemia.