SALL4 and acute myeloid leukemia: As regard cases with SALL4 ≤1.0 RQ; we had 3 (21.4%) cases were AML with recurrent genetic abnormalities, 11 (78.6%) were AML not otherwise specified and as regard cases with SALL4 gene expression > 1.0 RQ, we had 4 (26.7%) were AML with recurrent genetic abnormalities, 8 (53.3%) were AML not otherwise specified and 3 (20%) were therapy related AML.