Numerous studies have shown that interleukin-1 beta (IL-1b), a pro-inflammatory cytokine in chronic inflammation has a higher level in several tumor site, including meningioma, which plays a critical role in tumor growth, metastasis, and angiogenesis (Apte et al., 2006; Multhoff et al., 2012). The gene discussed is IL1B; the disease is meningioma.