LGALS9 and glioblastoma: This depends on the enhanced expression of PD-L1, but no other immune checkpoint genes, such as B7-H3, herpesvirus entry mediator (HVEM), and galectin-9 (LGALS9), suggesting that TMZ controls the expression of PD-L1 in glioblastoma cells, resulting in the evasion of the immune system [41].