CDKN2B-AS1 and cancer: Modified CRISPR systems could also generate the substitution of cytidine into uridine in order to correct oncogenic SNPs, knowing that numerous single nucleotide polymorphisms (SNPs) have been associated with potential predictive biomarkers for the risk of cancer, including SNPs in ANRIL, MALAT1, HULC, and PRNCR1 lncRNA [168,169].