GAL and pachyonychia congenita: Considering the findings of cross-resistance between taxanes (docetaxel and carbazitaxel) and the new antihormonal drugs abiraterone and ENZ [19], the lack of impaired efficacy of Gal and the NGGAs in the ENZ- and DOC-resistant cell lines suggest that Gal/NGGAs can be developed to treat men with PC that become resistant to all four drugs currently registered for use in mCRPC.