FGF2 and infection: Intra-lesion injection of the recombinant form of EGF (rhEGF) directly at the site of the wound demonstrated a greater pharmacodynamic response in terms of granulation tissue growth and wound closure [44]; while PDGF-BB, FGFb, VEGF, and EGF were the most frequently used factors to improve the wound’s healing time, there were also clinical trials studying growth factors in the context of infection management.