Given that NF-κB and C/EBP-α gene expression and NF-κB methylation in VAT were correlated with CRC, we performed a multiple linear regression analysis to test the predictive value of NF-κB and C/EBP-α gene expression and NF-κB methylation in VAT as s risk marker for developing CRC. The gene discussed is NFKB1; the disease is colorectal carcinoma.