When data from all bronchopulmonary and gastroenteropancreatic neuroendocrine tumours were analysed together, significant differences were noted between patients with and without lymph node metastases, with higher GPR68 IRS values in patients with no lymph node metastases (without lymph node metastases: 1.854 ± 0.294; with lymph node metastases: 1.398 ± 0.210; Mann–Whitney test: p = 0.039). The gene discussed is GPR68; the disease is neuroendocrine neoplasm.