Additionally, in gastroenteropancreatic neuroendocrine neoplasms, a tendency towards lower GPR68 levels was observed in the metastases as compared to the primary tumours (primary tumours: 1.833 ± 0.241, metastases: 1.286 ± 0.252; Mann–Whitney test: p = 0.089). This evidence concerns the gene GPR68 and neuroendocrine neoplasm.