The chromosomal analysis from comparative genomic hybridization (CGH) of the BCL-2 family members identified frequent deletions of pro-apoptotic BAK, BID, and BAD loci, and overexpression of anti-apoptotic BCL-2 and BCL-XL in several tumors including childhood cancers—glioblastoma and acute leukemias [68]. Here, BCL2L1 is linked to childhood malignant neoplasm.