ESR1 and breast carcinoma: Peng et al. (2017) were able to demonstrate that Linc-RoR (long intergenic non-protein-coding RNA, regulator of reprogramming), a gene that produces a long non-coding RNA regulating the reprogramming of pluripotent stem cells, functions as an onco-lncRNA to specifically promote this estrogen-independent growth of ER+ breast cancer.