Despite the lack of biochemical measurement of lipid in both liver and blood, which can clarify lipid dynamics in vivo, we demonstrated that a decline in both cd36 mRNA and CD36 abundance in miR-29aTg group fed with HF diet is compatible with decreased normalized liver weight and liver lipid accumulation determined by IHC compared to WT group, supporting the notion that blunting liver CD36 may reduce hepatocellular steatosis. The gene discussed is CD36; the disease is hydrops fetalis.