We identified vascular endothelial growth factor A (VEGFA, also known as VPF, VEGF, or MVCD1) as a MIR452 target gene in CRC, and analyzed the correlation between MIR452 and VEGFA using human CRC tissues, cell lines, and xenograft tumors, as well as rat aortas. This evidence concerns the gene VEGFA and colorectal carcinoma.