The two closest ones (Tanimoto index around 0.7) are presented in Figure 16: the first one is described in PubChem (MLS00073044 and CID 16195204) and was tested in bioassays against the protein target huntingtin (Huntington disease) and the second compound was described in US patent 2010/0267671A1 to modulate apoptosis in cells. Here, HTT is linked to Huntington disease.