PPP1R14B interacts with ROCK2 (“IntAct” EBI-7009696), which is a key regulator of the actin cytoskeleton and cell polarity and is one of the most highly overexpressed phosphatase-related proteins in triple-negative breast cancer (TNBC), which has the worst prognosis among all breast cancers [40]. This evidence concerns the gene PPP1R14B and breast cancer.