TP73 and neoplasm: Mechanistically, TP73-AS1 modulated the tumor progression of GC cells through several signaling pathways, involving targeting miR-194-5p/SDAD1, down-regulation of HMGB1/RAGE, and regulating Bcl-2/caspase-3 or reversing epithelial-to-mesenchymal transition (EMT) [25–27].