LncRNAs act as either suppressors or promoters in various cancers, including osteosarcoma [4,5], ovarian cancer [6], gastric cancer [7], glioma [8], breast cancer [9], colorectal cancer [10], hepatocellular carcinoma [11] etc. Among many lncRNAs investigated, tumor suppressor candidate 7 (TUSC7) was reported as a novel cancer suppressor gene [4,8,12]. This evidence concerns the gene TUSC7 and osteosarcoma.