ACADS and hepatocellular carcinoma: Figure 5C depicts our findings which note that as compared to the patients with low levels of ACADS DNA methylation, the patients with high DNA methylation levels of the ACADS gene were associated with a worse 2-, 5-, and 10-year survival rate among the patients with HCC. And based on the methylation level of ACADS, we established the nomogram of HCC using TCGA database (Supplementary Figure 2B).