FABP4 and neoplasm: Shen et al. and Sayagués et al. explored the expression of FABP4 in patients with CRC by microarray analysis, the former studies showed that decreased FABP4 gene expression was identified from tumor samples compared with adjacent non-cancerous controls [19], the latter studies revealed that FABP4 expression levels are normal from primary tumors in CRC, whereas FABP4 expression is reduced of liver metastases from CRC patients [30].