The suitability of trabeculectomy specifically in JIA-related uveitic glaucoma was highlighted in a retrospective study of 21 children showing good IOP control and an overall success rate (with topical anti-glaucoma medication) of 71.4% after 5 years.39 Leinonen et al.40 examined the results of the potential effect of treatment with systemic tumor necrosis factor (TNF) inhibitor on the success of an MMC-augmented trabeculectomy for individuals with JIA-related uveitic glaucoma. This evidence concerns the gene TNF and glaucoma.