TNF and arthritic joint disease: Cytokine inhibitors have been reported to achieve significant success rates in several types of arthritis and other inflammatory diseases (e.g., Crohn’s disease) in children and therefore their use has been seriously considered for the treatment of uveitis as well.2 Until recently, etanercept (Enbrel, Immunex Corporation, Seattle, Washington, USA) and infliximab (Remicade, Centocor, Inc., Malvern, Pennsylvania, USA), which inhibit tumor necrosis factor (TNF), were the two main biological agents evaluated for patients with uveitis.