Thus in anti‐NMDAR encephalitis, autoantibodies induce receptor cross‐linking and internalization, in anti‐LGI1 encephalitis autoantibodies interfere with protein–protein interactions, and in anti‐GABABR encephalitis autoantibodies may block the function of the target antigen (Hughes et al., 2010; Ohkawa et al., 2013). This evidence concerns the gene LGI1 and encephalitis.