For example, pericytes that express a missing protein (dystrophin in DMD) or lack the RNA gain-of-function mutation (repeat expansion in DM1) may be systemically administered.8, 54, 55 Autologous pericytes can infiltrate multiple target tissues from the circulation in response to cytokines released by dystrophic muscle. The gene discussed is DMD; the disease is myotonic dystrophy type 1.