In present work, the biomarkers of bone resorption (BGLAP, TRAP, and CTX-1) or bone formation (BALP, and INTP) in serum reduced in goat group under nutrient restriction, indicating maternal malnutrition indeed influences the maternal or fetal bone metabolic turnover (Kovacs, 2001; Wu et al., 2004; Wu, Imhoff-Kunsch & Girard, 2012). The gene discussed is BGLAP; the disease is malnutrition.