Evaluation of the treatment of UMUC-3, TCCSUP, and RT-112 bladder cancer cell lines with amygdalin at concentrations of 1, 10, 25 mg/ml using the Annexin-V-FITC/PI kit showed  a dose-dependent relationship between amygdalin concentration and Annexin V positive cells   7  . This evidence concerns the gene ANXA5 and urinary bladder cancer.