Moreover, Ellis et al. (2013) tried to find differences between HF patients and non–HF-related breathlessness, and between HFrEF and HF with preserved ejection fraction (HFpEF); although they found a differential expression of miR-103, miR-142-3p, miR-30b, and miR-342-3p in HF and breathless patients, individually, classical biomarkers such as NT-proBNP and hs-cTnT exhibited greater sensitivity and specificity. Here, NPPB is linked to hydrops fetalis.