TNNI3 and myocardial infarction: Currently, the favored diagnostic biomarkers of AMI are cardiac troponin I (cTnI) and T (cTnT), both of which are released from necrotic cardiomyocytes within 2 to 4 h post-MI (Babuin and Jaffe, 2005), with maximum levels at 24 to 48 h and lasting for more than 1 week (Jaffe et al., 2006).