Nevertheless, in another study analyzing miR-133a and miR-423-5p and their relationship with cardiac biomarkers, such as B-type natriuretic peptide (BNP), C-reactive protein, and cTnI in MI patients, an increase in circulating levels of both miRNAs was observed, but these changes were not associated with LV remodeling or BNP. This evidence concerns the gene TNNI3 and myocardial infarction.