It is peculiar that some Huh7.5-specific sponge-like RNAs, including those for alpha-fetoprotein (AFP) (Parpart et al., 2014) and APOB (Bi et al., 2014), were previously described as biomarkers of liver carcinoma, a tissue of origin for Huh7.5 cell line. This evidence concerns the gene AFP and hepatocellular carcinoma.