Unexpectedly, no significant change in the amount of GZMB+ cells was found between pre- and post-treatment tumor biopsies (mean ± SEM 118.3 ± 47.68 vs. 137.2 ± 51.98 GZMB+ cells/mm2 in pre-treatment and post-treatment biopsies, respectively; p = 0.5830; Figure 3B). The gene discussed is GZMB; the disease is neoplasm.