Based on our results and the high frequency of the T allele in the Han Chinese population, it seems that while the association between NRG1 rs6994992 and schizophrenia is more subject to allele frequency of the T allele (the risk for schizophrenia mediated by the T allele might be masked by the high frequency of the T allele in the Han Chinese population), the association between NRG1 rs6994992 and creativity is not affected by allele frequency of the T allele and thus more consistent across different ethnic populations. Here, NRG1 is linked to schizophrenia.