Accessible fluid biomarkers could be more useful for assessing the presence of CTE Cerebrospinal fluid (CSF) measures of total tau (t-tau), p-tau, and amyloid-β peptide (Ab) are widely accepted as diagnostic and prognostic biomarkers for AD (Meredith et al., 2013; Galasko and Shaw, 2017). Here, MAPT is linked to Alzheimer disease.