ZIC2 and posterior cortical atrophy: Matrigel assay was used to analyze the impact of miR-129-5p expression on angiogenesis of PCa cells, and the results (Fig. 7a, b) showed that, the miR-129-5p mimic and si-ZIC2 groups showed significantly decreased angiogenesis (p < 0.05), while miR-129-5p inhibitor group showed significantly enhanced angiogenesis (p < 0.05) when compared to the blank and NC groups.