ZIC2 and posterior cortical atrophy: RT-qPCR was used quantify the expression of miR-129-5p, ZIC2, Wnt, and β-catenin in adjacent normal tissues and PCa tissues, and the results (Fig. 2a) showed that compared with the control group, the expression of miR-129-5p in the PCa group was markedly decreased, but the mRNA expression of ZIC2, Wnt, and β-catenin was significantly increased (all p < 0.05).