Immunohistochemistry was used to analyze the expression of Wnt3a and β-catenin in PCa tissues (Fig. 2b, c), which revealed that the positive expression rates of Wnt3a and β-catenin in adjacent normal tissues were 13.33% and 36.67%, respectively, whereas these rates in the PCa tissues were 73.33% and 93.33%, respectively. Here, WNT3A is linked to posterior cortical atrophy.