qRT-PCR analyses revealed a high expression of three Cxs: Cx25, Cx31.9, and Cx59 in all AML primary samples with ΔCt values varying from 6 to 9 for Cx25, 7 to 10 for Cx31.9, and 7 to 10 for Cx59 (Fig. 1a). Here, GJB7 is linked to acute myeloid leukemia.