CD4 and infection: Viral gRNA levels were detectable in CD4+ T cells on days 1 and 2 post infection at approximately 1x105 copies/mg followed by some decrease at day 5 (Fig 1A); comparable levels of gRNA were detected in Jurkat cells (S1 Fig). Viral mRNA was detected in both CD4+ T cells and the Jurkat cells cultured with EBOV (Fig 1B–1E and S1 Fig).