MALAT1 and glioblastoma: MALAT1, first discovered as a predictive factor for metastasis in early-stage, non-small cell lung cancer,25 was revealed to be one of the highly expressed lncRNAs in GBM tissues and corresponded to poor prognosis for GBM patients.26, 27, 28, 29 Additionally, recent studies have highlighted MALAT1’s potential role as a competing endogenous RNA (ceRNA), a class of miRNA that is capable of serving as a “molecular sponge” for smaller miRNAs, thereby modulating their downstream functions.30, 31, 32