The analysis of individual interactions within this miRNA regulatory network may yield findings to suggest that a specific lncRNA may play both a tumor suppressor and tumor promoter role in different cancer types, depending on the specific regulatory networks considered.37, 38 In our investigation, we specifically directed our focus on determining the role of MALAT1 in the regulation of miR-199a and its downstream target, ZHX1. This evidence concerns the gene MALAT1 and cancer.