No association of the CTSG N125S polymorphism with type of bone infection (acute vs. chronic) (p = 0.7), source of infection (hematogenous vs. non hematogenous, p = 0.9), (pressure ulcers vs. non pressure ulcers, p = 0.5) or microorganism isolated (S. aureus vs. Gram negative bacteria p = 0.9) was found. Here, CTSG is linked to infection.