Altered gene expression of monocarboxylate transporter 4, (SLC16A4) has been found in the spinal cord of hSOD1G93A mice (Ferraiuolo et al., 2011a) and the oligodendrocytic lactate transporter monocarboxylate transporter 1 (SLC16A1) was decreased in the spinal cords of ALS cases and SOD1G93A mice (Lee et al., 2012b; Philips et al., 2013). The gene discussed is SLC16A4; the disease is amyotrophic lateral sclerosis.