ITSN1 and ischemia: Possible explanations for these results might be that lnc‐ITSN1‐2 upregulated several inflammatory cytokines (including TNF‐α, IL‐6, and IL‐8) and inflammation‐related pathways (including NF‐κB and TRL pathways) to advocate inflammation, which subsequently increased the vascular damage and altered the vascular structure, thereby leading to elevated risk in ischemia, which resulted in the enhanced risk of AIS.