In order to evaluate the potential of lnc‐ITSN1‐2 as a biomarker for monitoring disease severity in AIS patients, NIHSS score was assessed and the correlation between lnc‐ITSN1‐2 expression and NIHSS score was performed, which displayed that lnc‐ITSN1‐2 expression was positively associated with NIHSS score in AIS patients (r = 0.464, P < .001; Figure 2). The gene discussed is ITSN1; the disease is androgen insensitivity syndrome.