Reasons for not being eligible included BMI < 25 (n = 29), current use of OCP (n = 37), use of insulin sensitisers (n = 34), use of gonadotrophins (n = 4), unable to attend (n = 10), has diabetes (n = 7), did not meet PCOS diagnostic criteria (n = 6), has another hormonal condition (n = 11), pregnant (n = 5) within age range (n = 3). The gene discussed is INS; the disease is polycystic ovary syndrome.