UBE2C is essential for mitotic cyclins and regulating anaphase‐promoting complexes.33, 34 Overexpression of UBE2C may cause chromosome missegregation and change the cell cycle profile, which facilitates cell proliferation.6, 35 Thus, UBE2C would be a potential biomarker for tumor diagnosis or prognostic determination. This evidence concerns the gene UBE2C and neoplasm.