In 2007, Porkka et al reported the specific expression of miRNA in patients with PCa for the first time.36 Currently, various miRNAs from circulating blood can be used as markers for the diagnosis and prognosis of PCa patients.37, 38, 39 Herein, the luciferase assay indicated that miR‐381‐3p targeted UBE2C directly in both LNCaP and PC‐3 cells. Here, UBE2C is linked to posterior cortical atrophy.