We evaluated whether expression of some of the genes selectively regulated in AD, such as Duox1, Il13ra2, Stac2, as well as other genes implicated in AD pathogenesis in mice or humans such as Tslp, Aqp3, Il4ra, Nod2, Osm, Slc4a11, Mmp13, and Serpinb3 were altered in JunBΔep mice (Olsson et al., 2006, Cianferoni and Spergel, 2014, Miyai et al., 2016, Weidinger et al., 2018). The gene discussed is AQP3; the disease is Alzheimer disease.