MMP7 and colorectal carcinoma: First, this is the biggest and mostrecent meta-analysis of the association of MMP-7 -181A>G polymorphism with CRCand GC risk, and it was more powerful than previous single case-control studies.Second, this is the first meta-analysis by subgroup analysis showed that the MMP-7-181A>G polymorphism was associated with CRC risk in Asians.