RNASE2 and cancer: Some of the more prominent of these homologs are the eosinophil-derived neurotoxin (RNase 2), and eosinophil cationic protein (RNase 3), which have been implicated in hypereosinophilic and allergic conditions, and angiogenin (RNase 5), which induces neovascularization during normal organ growth, cancer, and in vascular and rheumatoid disorders [3].