Relative to luminal B subtype, breast cancers in the central zone were less likely to be HER2‐overexpressing subtype (multivariate‐adjusted OR = 0.48, 95% CI: 0.24‐0.94), and breast cancers in the UIQ were more likely to be luminal A subtypes (multivariate‐adjusted OR = 2.44, 95% CI: 1.20‐4.99). This evidence concerns the gene ERBB2 and breast carcinoma.